Clinical Development Leader, Epilepsies

About this role

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Turning promising science into better treatments for epilepsy takes more than expertise. It takes ownership, sound judgment, and the drive to lead trials and translate emerging data into decisions that move medicines forward for the patients we serve. At Praxis, you’ll take clinical leadership across our epilepsy portfolio, spanning adult programs and pediatric studies. You’ll shape development strategy, lead studies, interpret emerging data, drive cross-functional execution, and carry clinical strategy through regulatory submissions and health authority interactions. This is a role for someone who is hands-on and wants to lead the work, not just review and advise on the work of others. You bring deep epilepsy development experience while also helping build the capabilities of other clinical leaders across the portfolio.

Primary Responsibilities

• Epilepsy development: Apply deep understanding of adult and pediatric epilepsy, trial design, endpoints, and the regulatory pathway – including pediatric requirements such as PIP and PSP – to development strategy and decision-making.

• Clinical strategy and trials: Translate science, emerging data, patient need, and regulatory requirements into development strategies – and personally lead studies from design through execution.

• Data-driven decisions: Interpret emerging clinical and scientific data, identify what matters, and make timely calls when information is incomplete.

• Regulatory strategy: Own substantive clinical content for regulatory filings, briefing materials, and health authority interactions.

• Cross-functional leadership: Drive teams across clinical operations, biostatistics, regulatory, safety, and other disciplines to resolve issues and move programs forward.

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